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Dog Genetics in 2025: What your dog’s DNA can tell you about their health - Paw Print Health

Dog Genetics in 2025: What your dog’s DNA can tell you about their health

Sep 09

Genetics is one of the fastest growing areas in dog health. New research is helping us understand how a dog’s DNA influences everything from weight and skin issues to how their body responds to food. At Paw Print, we believe genetics is the foundation for proactive care that gives dogs more happy, healthy years.


Why genetics matters now

Large global projects like Dog10K have been mapping thousands of canine genomes. This work gives us better insight into breed traits, disease risks, and how genes interact with lifestyle and diet. One recent study found that more than half of all dogs carry at least one gene linked to a disease. That does not mean every dog will get sick, but it does highlight how important it is to know what is in your dog’s DNA.


A new discovery about weight

A study published this year by a Cambridge team identified a gene called DENND1B that is linked to body fat in Labradors. Dogs with this gene are more likely to gain weight because of how their brains regulate appetite. The good news is that diet and exercise still play a powerful role. Genetics can raise the risk, but it does not set the outcome. For owners, knowing your dog’s risk helps you make smarter choices about feeding and daily activity.


Skin and gut health: where genes, food and microbes meet

Some skin and gut conditions have a genetic component, but they are also shaped by diet and the bacteria that live in your dog’s gut. Studies show that allergic dogs often have different microbiomes compared to healthy dogs. That means genetics, food intolerances, and gut balance all interact. By looking at all three, you get a clearer picture of what may be driving issues like itchy skin, loose stools, or low energy.


What a DNA test can reveal

A dog DNA test today can show you:

  • Breed mix and ancestry

  • Known genetic risks for conditions such as drug sensitivities or metabolic issues

  • Traits like coat type, body size, and behavior tendencies

What it cannot do is give absolute predictions. Most common conditions involve multiple genes and lifestyle factors. Genetics shows the risk, but daily choices about food, weight, and environment determine the outcome.


How Paw Print turns DNA into action

At Paw Print, we combine three tests to give you the full picture:

  1. DNA Test – understand your dog’s breed mix and genetic risks

  2. Intolerance Test – uncover hidden food or environmental triggers

  3. Gut Health Test – measure the balance of bacteria that influence digestion and immunity

Our vets then create a personalised plan that brings these results together. That plan includes nutrition advice, supplement options, weight targets, and practical steps you can use every day.


Key questions answered

Are mixed breed dogs healthier than purebreds?
Not always. Both mixed breed and purebred dogs can carry genetic risks. What matters is knowing which ones and managing them well.

Can genetics explain obesity?
Yes, some genes influence appetite and weight gain. But even dogs with those genes can stay at a healthy weight with the right feeding routine.

Can changing food help with itchy skin?
Yes, often. Genetics may create the tendency, but food and gut balance usually determine whether symptoms appear.


The bottom line

Genetics sets the stage. Your choices as an owner write the story. By combining DNA insights with intolerance and gut testing, you can take control of your dog’s future health instead of leaving it to chance.

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